Wegener’s Granulomatosis Granulomatosis and Polyangiitis
Axial CT of the chest (upper: soft tissue windows, lower: lung windows) in a 70-year-old woman with GPA demonstrates necrotizing pneumonia in the left upper lobe and additional bronchopneumonic ground-glass opacities in the right upper lobe and superior segment of the left lower lobe. There is associated mediastinal shift due to parenchymal volume loss, reflecting the destructive sequelae of small-vessel vasculitis and necrotizing inflammation.
Ashley Davidoff MD – TheCommonVein.com (140619.lungs) 003Lu
Axial CT chest in a patient with GPA demonstrates extensive ground-glass opacity in the left lower lobe, most consistent with diffuse alveolar hemorrhage. In addition, there is nodular consolidation in the right lower lobe, a pattern typical of vasculitic granulomatous inflammation. These findings illustrate the dual manifestations of GPA: hemorrhagic small-vessel involvement and necrotizing nodular parenchymal disease.
Ashley Davidoff MD – TheCommonVein.com (140620.lungs) 003Lu
Axial CT of the lower lobes in a 70-year-old woman with GPA (Wegener’s granulomatosis) demonstrates consolidation in the lingula and left lower lobe with probable small foci of cavitation. The right lower lobe shows peribronchial thickening, reflecting airway-centered inflammatory involvement. These findings, documented one year prior, highlight the multifocal and destructive nature of GPA, combining parenchymal necrosis with airway inflammation.
Ashley Davidoff MD – TheCommonVein.com (140622) (003Lu)
MIP coronal CT demonstrates extensive ground-glass opacity and consolidation throughout the left lung with associated volume loss. The right lung shows patchy ground-glass opacities involving the mid and lower zones. These findings, seen one year prior, reflect the diffuse hemorrhagic and inflammatory parenchymal involvement characteristic of GPA, with progressive destructive changes more advanced on the left.
Ashley Davidoff MD – TheCommonVein.com (140624) (Case 003Lu)