Position of Disease
Basilar and peripheral distribution
Ashley Davidoff MD TheCommonvein.net lungs-0769b
CT UIP –                                                                                                                                                                                84-year-old man presenting with dyspnea.                                                                                                              Axial CT at the lung bases demonstrates asymmetric fibrotic changes, right worse than left, with peripheral honeycombing at the right base.  At the left base there  is subpleural arching fibrosis as a result of thickening of interlobular septa  along with reticulations and  architectural distortion. These findings are characteristic of Usual Interstitial Pneumonia (UIP), consistent with Idiopathic Pulmonary Fibrosis (IPF).
Editorial Comment: UIP is characterized by a spatially and temporally heterogeneous pattern of fibrosis, predominantly in the lower lobes, subpleural regions, and peripheral lung zones. The presence of honeycombing, architectural distortion, and reticulation suggests advanced disease. The asymmetric nature of fibrosis in this case, with a dominant right-sided involvement, highlights potential variability in disease progression or co-existing contributing factors.      Ashley Davidoff MD TheCommonVein.com (136453)
CT UIP
84-year-old man presenting with dyspnea
Axial CT at the lung bases demonstrates asymmetric fibrotic changes, right worse than left, with peripheral honeycombing at the right base.  At the left base there  is subpleural arching fibrosis as a result of thickening of interlobular septa  along with reticulations and  architectural distortion. These findings are characteristic of Usual Interstitial Pneumonia (UIP), consistent with Idiopathic Pulmonary Fibrosis (IPF).
Editorial Comment: UIP is characterized by a spatially and temporally heterogeneous pattern of fibrosis, predominantly in the lower lobes, subpleural regions, and peripheral lung zones. The presence of honeycombing, architectural distortion, and reticulation suggests advanced disease. The asymmetric nature of fibrosis in this case, with a dominant right-sided involvement, highlights potential variability in disease progression or co-existing contributing factors.     
The 2 people with arms in the shape of U’s surrounding the peripheral regions of the lungs reflect the portray the peripheral nature of the disease
Ashley Davidoff MD TheCommonVein.com (136453-01s)
CT UIP
84-year-old man presenting with dyspnea
Axial CT at the lung bases demonstrates asymmetric fibrotic changes, right worse than left, with peripheral honeycombing at the right base.  At the left base there  is subpleural arching fibrosis as a result of thickening of interlobular septa  along with reticulations and  architectural distortion. These findings are characteristic of Usual Interstitial Pneumonia (UIP), consistent with Idiopathic Pulmonary Fibrosis (IPF).
Editorial Comment: UIP is characterized by a spatially and temporally heterogeneous pattern of fibrosis, predominantly in the lower lobes, subpleural regions, and peripheral lung zones. The presence of honeycombing, architectural distortion, and reticulation suggests advanced disease. The asymmetric nature of fibrosis in this case, with a dominant right-sided involvement, highlights potential variability in disease progression or co-existing contributing factors.     
The 2 U’s reflect the asymmetric nature and the peripheral nature of the disease
Ashley Davidoff MD TheCommonVein.com (136453-00b)
CT UIP
84-year-old man presenting with dyspnea
Axial CT at the lung bases demonstrates asymmetric fibrotic changes, right worse than left, with peripheral honeycombing at the right base.  At the left base there  is subpleural arching fibrosis as a result of thickening of interlobular septa  along with reticulations and  architectural distortion. These findings are characteristic of Usual Interstitial Pneumonia (UIP), consistent with Idiopathic Pulmonary Fibrosis (IPF).
Editorial Comment: UIP is characterized by a spatially and temporally heterogeneous pattern of fibrosis, predominantly in the lower lobes, subpleural regions, and peripheral lung zones. The presence of honeycombing, architectural distortion, and reticulation suggests advanced disease. The asymmetric nature of fibrosis in this case, with a dominant right-sided involvement, highlights potential variability in disease progression or co-existing contributing factors.     
The 2 people with arms in the shape of U’s surrounding the peripheral regions of the lungs reflect the portray the peripheral nature of the disease. The 2 U’s with different fonts reflect the asymmetric nature and the peripheral nature of the disease
Ashley Davidoff MD TheCommonVein.com (136453-02s)
CT UIP
Artistic rendering of the CT of an 84 year old man s demonstrates asymmetric fibrotic changes, right worse than left, with peripheral honeycombing on the left .  On the  right base there  is subpleural arching . These findings are characteristic of Usual Interstitial Pneumonia (UIP), consistent with Idiopathic Pulmonary Fibrosis (IPF).
Editorial Comment: UIP is characterized by a spatially and temporally heterogeneous pattern of fibrosis, predominantly in the lower lobes, subpleural regions, and peripheral lung zones. The presence of honeycombing, architectural distortion, and reticulation suggests advanced disease. The asymmetric nature of fibrosis in this case, with a dominant right-sided involvement, highlights potential variability in disease progression or co-existing contributing factors.     
Ashley Davidoff MD TheCommonVein.com (139938-02)
Aymmetric U’s in Art
Designed in Collaboration with AI
Ashley Davidoff MD The CommonVein.com (139923)
Aymmetric U’s in Art
Designed in Collaboration with AI
Ashley Davidoff MD The CommonVein.com (139924)
Aymmetric U’s in Art
Designed in Collaboration with AI
Ashley DAvidoff MD The CommonVein.com (139930)
Aymmetric U’s in Art
Designed in Collaboration with AI
Ashley Davidoff MD The CommonVein.com (139926b)

 

 

Honeycomb Lung
In patients with interstitial lung  disease, the  inflammatory process and interstitial fibrotic disease  progresses and the walls between the alveoli are destroyed causing large subpleural, variably sized, subpleural, thick walled, stacked, cystic spaces . The appearance is reminiscent of a honeycomb and indicates end stage fibrosis
Ashley Davidoff MD thecommonvein.net lungs-0738bh